Soothe itchy skin fast with BENADRYL Extra Strength Itch Relief Stick, an easy-to-apply antihistamine topical analgesic stick with 2% diphenhydramine HCI and 0.1% zinc acetate skin protectant to help protect your skin. Apply directly on skin to treat pain and itching associated with most outdoor causes of itching skin such as insect and mosquito bites, minor burns, sunburn, minor skin irritations, minor cuts, scrapes, skin rashes due to poison ivy, poison oak, and poison sumac.